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Dermatotoxicology
The structure of the text has also been reorganized to enable easier location of a topic of interest. With contributions from leading international experts, this continues the tradition of providing unsurpassed theoretical and practical guidance for all those working on research aspects, on practical clinical issues, and on the regulatory aspects of exposure to toxic substances. This new edition contains updates to each chapter and contributions from leading international experts, provides an in-depth summary of research and regulatory applications related to dermal toxicology and pharmacology, presents many new chapters that describe the latest advances in dermatotoxicology, and addresses various levels of expertise regarding the development and use of dermal exposure data.
New chapters include those on safety terminology, pharmacogenetics and dermatology, ethnic differences in skin properties, and the principles and practice of percutaneous absorption.
Dermatotoxicology: 8th Edition (Hardback) - Routledge
Pharmacogenetics and dermatology 2. Hormesis and dermatology 3. Toward an evidence-based dermatotoxicology 4.
How to improve skin notation 5. Skin ion channels in health and disease II: Nephrotoxicity of organic solvents from skin exposure 9.
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Mechanisms in cutaneous drug hypersensitivity reactions Systemic allergic contact dermatitis III: Immunological mechanisms in irritant and allergic contact dermatitis Contact urticaria syndrome IV: Chemical warfare agents Allergic contact dermatitis from ophthalmics Textiles and human skin, microclimate, and cutaneous reactions: Identifying the source of textile-dye allergic contact dermatitis: Chemical agents that cause depigmentation Factors influencing applied amount of topical preparations Immune reactions to copper Sodium lauryl sulfate In vivo human transfer of topical bioactive drugs among individuals: Depigmentation changes as a result of arsenic exposure V: Susceptibility of Different Populations Gender and pharmacokinetics Dermatological drug usage in the elderly A valid syndrome of multiple origins Dermatotoxicology of the vulva Human scalp irritation related to arm and back Functional map and age-related differences in human faces: Adhesive tape stripping reveals differences in stratum corneum cohesion between Caucasians, Blacks and Hispanics as a function of age VI: Animal, human, and in vitro test methods for predicting skin irritation Physiologically based pharmacokinetic modelling of dermal absorption In vitro approaches to assessment of skin irritation and phototoxicity of topically applied materials The local lymph node assay Utilization of irritation data in local lymph node assay Failure of standard test batteries for detection of genotoxic activity of some chemicals used in dermatological and cosmetic products Determination of chromium and nickel allergy, sensitization, and toxicity by cellular in vitro methods Methods for in vitro skin metabolism