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- Hypothyroidism and the Heart.
- Untreated Hypothyroidism, Thyroid Hormone, and Cardiac Effects.
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Thyroid hormone: How it affects your heart
Alexa Actionable Analytics for the Web. AmazonGlobal Ship Orders Internationally. Ladenson, who emphasized the seminal contributions of Dr. Chester Chip Ridgway to these aspects of thyroidology. Effects of thyroid hormone deficiency can lead to heart failure—usually due to exacerbation of intrinsic cardiac disease, but occasionally due to hypothyroidism alone. Mechanisms include bradycardia, reduced left ventricular contractility, diastolic dysfunction, and increased systemic resistance. This is a reversible form of cardiomyopathy with recovery over a period of weeks after initiation of levothyroxine therapy.
Secondary Hypercholesterolemia Hypothyroidism is also a common cause of secondary hypercholesterolemia with its associated ischemic heart disease risk. This effect occurs not only in overt hypothyroidism, but also in mild or subclinical hypothyroidism. Hak et al, Ann Int Med , Similarly, prospective studies have shown that subclinical hypothyroidism raises risk of coronary heart disease CHD events and mortality. A total of participants 6. Risk of CHD events and mortality were higher among those with higher thyroid stimulating hormone concentrations, even after adjusting for traditional cardiovascular risk factors.
Untreated Hypothyroidism, Thyroid Hormone, and Cardiac Effects
Conclusion Hypothyroidism reversibly impairs left ventricular function and can even cause heart failure. Even mild hypothyroidism can impair left ventricular performance and cause hypercholesterolemia, raising the risk of CHD events and death. Levothyroxine therapy can reverse impaired myocardial performance as well as dyslipidemia due to thyroid hormone deficiency.
Thyroid Hormone and the Heart. Chester Ridgway Memorial Thyroid Symposium.