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But when you drink wine and beer you'll feel queer. If the answer is yes, why? From my experiences, and those of my friends, I can attest to the accuracy of the rhyme but cannot explain it. John Charnock, Warrington UK There is no proof that mixing wine or beer has any effect on sexual preference, no matter in which order they are drunk.
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Sexual performance on the other hand If you change your tipple mid-way through the evening, because your palate will be desensitised to by? A pint or two of wine will cause a bigger hangover than a wineglass or two of beer!
Don't know why, though! The explanation I heard for it was that if you start on shorts when you've already had a skinful of beer you'll drink more of them, and more quickly, because you'll already be drunk and your self-control will be reduced. Julian, Bristol UK Here's one possible explanation that can be applied to all sorts of drinking situations: Normally this is closed, opening at regular intervals to allow food etc through.
When you drink a fizzy drink the bubbles will form on the stomach lining similar to how they form on the side and bottom of a glass. These bubbles stimulate the pyloric sphincter muscle and cause it to open allowing food and drink into the intestine. The intestine has a much higher surface area to volume ratio than the stomach which allows much increased absorption of nutrients etc including alcohol. When you have been drinking wine this will sit in the stomach and is slowly released into the intestine. If you then drink a fizzy drink, such as beer, this opens the sphincter muscle and allows beer AND wine into the intestine.
This cocktail is rapidly absorbed and everything goes a bit "queer". If you drink the beer first then the same thing happens except that the cocktail entering the intestine is just beer and therefore "all fine". Subsequent wine consumption will be absorbed more slowly since the sphincter would then be working normally. Incidentally, this is the same mechanism by which Champagne goes "straight to your head". Beer after wine is to be avoided, wine after beer is advised.
Personally I try not to mix them in any order!