Get free access to newly published articles Create a personal account or sign in to: Register for email alerts with links to free full-text articles Access PDFs of free articles Manage your interests Save searches and receive search alerts. Sign in to save your search Sign in to your personal account. Create a free personal account to access your subscriptions, sign up for alerts, and more. Purchase access Subscribe now. Sign in to customize your interests Sign in to your personal account. Create a free personal account to download free article PDFs, sign up for alerts, customize your interests, and more.

Sign in to make a comment Sign in to your personal account.

Also Available As:

Neurological Injury from Undersea Diving, E. Lightning Injuries, Michael Cherington Electrical Injuries, Mary Capelli-Schellpfeffer Posttraumatic Sequelae and Medicolegal Aspects Posttraumatic Syndromes, Christopher G. Goetz and Ilia Itin Tunkel and Alan R. Complications of Lumbar Puncture, Randolph W. Iatrogenic Nerve Injuries, Asa J. It addresses neurologists, neurosurgeons, and emergency physicians.

There are comprehensive sections on head trauma, spinal trauma, plexus and peripheral-nerve injuries, posttraumatic pain syndromes, enivornmental trauma, posttraumatic sequelae, and medicolegal aspects. The publication of this book has been carefully conceived and well executed.

The multiauthored monograph has been masterfully edited by R. The author has masterfully edited a comprehensive text on the neurologic implications of trauma.


  • Neurology and Trauma - Randolph W. Evans - Oxford University Press.
  • School Of Rock!
  • Neurology and Trauma!

It provides a valuable reference for those dealing with difficult complications of severe to mild injury. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

Academic Skip to main content. Choose your country or region Close. Ebook This title is available as an ebook. To purchase, visit your preferred ebook provider.

Mental Health, Neurology and Trauma

Praise for the first edition "This book is an excellent review of the neurology of trauma. MRI assessment of brain abnormalities in PTSD and trauma spectrum disorders Findings of smaller hippocampal volume appear to be associated with a range of trauma related psychiatric disorders, as long as there is the presence of psychological trauma.

Neural circuits in women with abuse and PTSD We have used PET to study neural circuits of traumarelated disorders in women with early abuse and a variety of trauma spectrum mental disorders. Treatment of PTSD Intervening soon after the trauma is critical for long-term outcomes, since with time traumatic memories become indelible and resistant to treatment. Neural correlates of fear conditioning in women with abuse and PTSD. There was increased amygdala activation with fear acquisition using a classical conditioning paradigm relative to nonPTSD abused women. PTSD, post-traumatic stress disorder.

Discussion Traumatic stress has a broad range of effects on brain function and structure, as well as on neuropsychological components of memory. Posttraumatic stress disorder in the national comorbidity survey. Posttraumatic stress disorder and major depressive disorder: Investigating the role of overlapping symptoms in diagnostic comorbidity. J Nerv Ment Dis. Course of illness and substance abuse.


  • Search form;
  • Pu Pu Hot Pot: The Worlds Best Restaurant Names;
  • The Ocean?
  • The Human Manual.
  • Software Endgames: Eliminating Defects, Controlling Change, and the Countdown To On-Time Delivery (Dorset House eBooks);

The clinical phenomenology of multiple personality disorder: Childhood maltreatment associated with adult personality disorders: Traumatic exposure and posttraumatic stress disorder in borderline, schizotypal, avoidant, and obsessive-compulsive personality disorders: The impact of adverse childhood experiences on health problems: New Freedom Commission Report: The Campaign for Mental Health Reform: A new advocacy partnership. Recommendations to transform mental health care in America. Anatomical MRI of the developing human brain: Brain development during childhood and adolescence: Structural and functional brain development and its relation to cognitive development.

Structural maturation of neural pathways in children and adolescents: Localizing age-related changes in brain structure between childhood and adolescence using statistical parametric mapping. Progressive cortical change during adolescence in childhood-onset schizophrenia: A longitudinal magnetic resonance imaging study. Growth patterns in the developing brain detected by using continuum mechanical tensor maps. Development of the normal human corpus callosum during childhood and adolescence: Prog Neuropsychopharmacol Biol Psychiatry.

Quantitative MRI of the temporal lobe, amygdala, and hippocampus in normal human development: Sexual dimorphism of the developing human brain. A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. Quantitative magnetic resonance imaging of human brain development: A controlled study of cortical gray matter and ventricular changes in alcoholic men over a 5year interval. Age-related decline in MRI volumes of temporal gray matter but not hippocampus. Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood.

Effect of estrogen on brain activation patterns in postmenopausal women during working memory tasks. Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Cerebellar volume decline in normal aging, alcoholism, and Korsakoff's Syndrome: Methods for measuring brain morphologic features on magnetic resonance images: Decreased gray matter in normal aging: Circuits and systems in stress.

Applications to neurobiology and treatment of PTSD. Does Stress Damage the Brain? The role of corticotropinreleasing factor in depression and anxiety disorders. Involvement of corticotropin-releasing factor in chronic stress regulation of the brain noradrenergic system. Noradrenergic mechanisms in stress and anxiety: Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. Adaptation to chronically presented stressful stimuli. Temporal and social factors influencing behavioral and hormonal responses to separation in mother and infant squirrel monkeys.

Effects of prenatal stress on vulnerability to stress in prepubertal and adult rats. Maternal deprivation potentiates pituitary-adrenal stress responses in infant rats. Persistent changes in CRF neuronal systems produced by maternal separation. Stress down-regulates corticosterone receptors in a site-specific manner in the brain.

Glucocorticoid-sensitive hippocampal neurons are involved in terminating the adrenocortical stress response. Regulation of corticotropinreleasing hormone receptor messenger-ribonucleic acid in the rat-brain and pituitary by glucocorticoids and stress. Increased expression of corticotropinreleasing hormone and vasopressin messenger-ribonucleic acid messenger RNA in the hypothalamic paraventricular nucleus during repeated stressassociation with reduction in glucocorticoid messenger-RNA levels.

Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult nonhuman primates exposed to early-life stressors: Implications for the pathophysiology of mood and anxiety disorders. Are the neural substrates of memory the final common pathway in PTSD? Functional neuroanatomical correlates of traumatic stress revisited 7 years later, this time with data.

"Trauma, Attachment & Neuroscience" Seminar with Bessel van der Kolk, M.D.

Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews. Paradoxical effects of adrenal steroids on the brain: Hippocampal damage associated with prolonged glucocorticoid exposure in primates.

Why stress is bad for your brain. Repeated stress causes reversible impairments of spatial memory performance. Psychological stress impairs spatial working memory: Relevance to electrophysiological studies of hippocampal function. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants.

Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex. Phenytoin prevents stress and corticosterone induced atrophy of CA3 pyramidal neurons. Stress, metaplasticity, and antidepressants. A molecular and cellular theory of depression. Regulation of adult neurogenesis by psychotropic drugs and stress. J Pharmacol Exp Ther. Molecular mechanisms of neuroplasticity and pharmacological implications: Tianeptine attenuates stressinduced morphological changes in the hippocampus.

Experience-induced neurogenesis in the senescent dentate gyrus. Learning enhances adult neurogenesis in the hippocampal formation. Effect of neonatal handling on age-related impairments associated with the hippocampus.

Neurology and Trauma

Maternal care, hippocampal synaptogenesis and cognitive development in rats. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. Injury severity, prior trauma history, urinary Cortisol levels, and acute PTSD in motor vehicle accident victims. Low urinary Cortisol excretion in holocaust survivors with posttraumatic stress disorder. Circadian regulation of basal Cortisol levels in posttraumatic stress disorder.

Ann NY Acad Sci. Cortisol regulation in posttraumatic stress disorder and major depression: Serial CSF corticotropin-releasing hormone levels and adrenocortical activity in combat veterans with posttraumatic stress disorder. Saliva Cortisol in posttraumatic stress disorder: A community epidemiologic study.

Salivary Cortisol and posttraumatic stress disorder in a low-income community sample of women. Marked lability of urinary free Cortisol levels in sub-groups of combat veterans with posttraumatic stress disorder. Cortisol and catecholamines in posttraumatic stress disorder: An epidemiological community study. Hypothalamic pituitary adrenal dysregulation in sexually abused girls. J Clin Endocrinol Metab. Abuse-related posttraumatic stress disorder: Evidence for chronic neuroendocrine activation in women.

Neurology and Trauma | JAMA | JAMA Network

Salivary Cortisol levels in children adopted from Romanian orphanages. The impact of child maltreatment and psychopathology on neuroendocrine functioning. Alterations in stress Cortisol reactivity in depressed preschoolers relative to psychiatric and no-disorder comparison groups. Enhanced dexamethasone suppression of plasma Cortisol in adult women traumatized by childhood sexual abuse. Cortisol response to a cognitive stress challenge in posttraumatic stress disorder PTSD related to childhood abuse.

Effects of dexamethasone on declarative memory function in posttraumatic stress disorder PTSD. Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood. Altered pituitary-adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse. Information processing and PTSD: A review of the empirical literature.

A cognitive neuroscience account of post-traumatic stress disorder and its treatment. Neuroendocrine activity and memory-related impairments in posttraumatic stress disorder. Attention and memory dysfunction in posttraumatic stress disorder. Deficits in short-term memory in post-traumatic stress disorder. Sustained attention in combatrelated posttraumatic stress disorder. Integr Physiol Behav Sci. Learning and memory in combat veterans with posttraumatic stress disorder. Memory and attention in posttraumatic stress disorder. J Psychopathol Behav Assess. Deficits in verbal declarative memory function in women with childhood sexual abuse-related posttraumatic stress disorder PTSD.

Deficits in short-term memory in adult survivors of childhood abuse. Multivariate assessment of explicit memory function in combat veterans with posttraumatic stress disorder. Learning and memory in rape victims with posttraumatic stress disorder. Everyday memory deficits in children and adolescents with PTSD: J Child Psychol Psychiatry. Complaints of impaired memory in veterans with PTSD. Attention, learning, and memory performance and intellectual resources in Vietnam veterans: PTSD and no disorder comparisons.

Cognitive functioning and posttraumatic stress disorder. Cognitive functioning in posttraumatic stress disorder. Memory, attention, function, and mood among patients with chronic posttraumatic stress disorder. Memory performance in Holocaust survivors with posttraumatic stress disorder. Learning and memory in aging combat veterans with PTSD.

J Clin Exp Neuropsychol. Memory functioning in adult women traumatized by childhood sexual abuse. Comparison of neuropsychological test performance in PTSD, generalized anxiety disorder, and control Vietnam veterans.