Long-term memory - information becomes a physical ‘thing’

When damage occurs in the occipital lobe it is most common to see the effects on the opposite side of the brain. Since the brain regions are so specialized in their functioning damages done to specific areas of the brain can cause specific type of damage. Damage to the left side of the brain can lead to language discrepancies, i. Many studies of different disease and disorders that have symptoms of memory loss have provided reinforcing evidence to the study of the anatomy of the brain and which parts are more utilized in memory.

Frontotemporal lobar degeneration FTLD is a common form of dementia due to the degeneration of the frontal and temporal lobes. Studies have found significant decreases in the essential needs for proper functioning in these lobes. The autobiographical domain in memory is largely affected by this disease. In one study, FTLD patients were interviewed and asked to describe a significant event from five different periods of their lives.

Using the interview and different methods of imaging, the experimenters hoped to find links between patterns of brain volume loss and performance in the interview.

Navigation menu

Through image processing, patterns of significant reduced parenchymal volumes that encompass the frontal and temporal lobes were found. Through comparison to a control group of patients it was found that parenchymal volumes increased during episodic recall, and decreased during semantic recall.

The experimenters discussed that lifespan autobiographical episodic recall was largely damaged in FTLD patients and semantic autobiographical memory seemed to be spared. Parkinson's disease involves both damage to the basal ganglia and certain memory dysfunctions, suggesting that the basal ganglia are involved in specific types of memory. Those who have this disease have problems with both their working memory and spatial memory.

Most people can instantly and easily use visual-spatial memory to remember locations and pictures, but a person with Parkinson's disease would find this difficult. He or she would also have trouble encoding this visual and spatial information into long-term memory.


  1. Microcontroller Programming: The Microchip PIC.
  2. Short-term memory – like writing your name with a sparkler.
  3. .
  4. .

People with Parkinson's disease display working memory impairment during sequence tasks and tasks involving events in time. They also have difficulty in knowing how to use their memory, such as when to change strategies or maintain a train of thought. From Wikipedia, the free encyclopedia. Fundamentals of Human Neuropsychology, 6th ed. The Student's Guide to Cognitive Neuroscience. The Journal of Neuroscience. New York Academy of Sciences. Annual Review of Neuroscience. Retrieved 17 March Anatomy of the descending pathways. The Nervous System, Handbook of Physiology, vol.

The organization of recent and remote memories. Some observations on prospective remembering. Current Research and Issues. Fundamentals of Human Neuropsychology. Principles of Neural Science. An analysis of short-term and long-term memory defects in man. The Physiological Basis of Memory.

Neuroanatomy of memory

Little, Brown and Company. Journal of Cognitive Neuroscience. Spatial updating in Parkinson's disease, Brain and Cognition, 23, Amnesia anterograde childhood post-traumatic psychogenic retrograde transient global Decay theory Forgetting curve Interference theory Memory inhibition Motivated forgetting Repressed memory Retrieval-induced forgetting Selective amnesia Weapon focus. Confabulation False memory Hindsight bias Imagination inflation List of memory biases Memory conformity Mere-exposure effect Misattribution of memory Misinformation effect Source-monitoring error Wernicke—Korsakoff syndrome.

A well-studied example of cerebellar motor learning is the vestibulo-ocular reflex, which lets us maintain our gaze on a location as we rotate our heads. The prefrontal cortex PFC is the part of the neocortex that sits at the very front of the brain. It is the most recent addition to the mammalian brain, and is involved in many complex cognitive functions. There also seems to be a functional separation between left and right sides of the PFC: Help QBI research Give now.

THE BRAIN FROM TOP TO BOTTOM

Skip to menu Skip to content Skip to footer. Site search Search Menu. Where are memories stored in the brain? The parts of the brain involved in memory Illustration by Levent Efe. Memory Types of memory How memories are formed Where are memories stored?

Implicit memory

What makes memories stronger? Memory and age Why you can't remember being a baby Factors affecting learning Learning: Neurons send messages to one another across narrow gaps called synapses.


  1. The Inhabited Ruins of Central Europe: Re-imagining Space, History, and Memory.
  2. I racconti dellEs (Gli emersi narrativa) (Italian Edition).
  3. How Our Brains Make Memories?
  4. The Politics of Sex Trafficking: A Moral Geography (Critical Criminological Perspectives)!
  5. What happens in your brain when you make a memory?.

A synapse is like a bustling port, complete with machinery for sending and receiving cargo—neurotransmitters, specialized chemicals that convey signals between neurons. All of the shipping machinery is built from proteins, the basic building blocks of cells. One of the scientists who has done the most to illuminate the way memory works on the microscopic scale is Eric Kandel, a neuroscientist at Columbia University in New York City. In five decades of research, Kandel has shown how short-term memories—those lasting a few minutes—involve relatively quick and simple chemical changes to the synapse that make it work more efficiently.

But after the memory is consolidated, it changes very little. Nader would challenge this idea. Nader got to wondering about what happens when a memory is recalled. Researchers had found that a memory could be weakened if they gave an animal an electric shock or a drug that interferes with a particular neurotransmitter just after they prompted the animal to recall the memory. This suggested that memories were vulnerable to disruption even after they had been consolidated. To think of it another way, the work suggested that filing an old memory away for long-term storage after it had been recalled was surprisingly similar to creating it the first time.

Both building a new memory and tucking away an old one presumably involved building proteins at the synapse. Nader decided to revisit the concept with an experiment. That was easy—rodents learn such pairings after being exposed to them just once. Afterward, the rat freezes in place when it hears the tone. But if memories have to be at least partially rebuilt every time they are recalled—down to the synthesizing of fresh neuronal proteins—rats given the drug might later respond as if they had never learned to fear the tone and would ignore it.

If so, the study would contradict the standard conception of memory. It was, he admits, a long shot. Nader, who looks slightly devilish in his earring and pointed sideburns, still gets giddy talking about the experiment. But the data struck a more harmonious chord with some psychologists.

The Anatomy of Memory - On Our Mind

After all, their experiments had long suggested that memory can easily be distorted without people realizing it. In a classic study led by Elizabeth Loftus, a psychologist then at the University of Washington, researchers showed college students a series of color photographs depicting an accident in which a red Datsun car knocks down a pedestrian in a crosswalk. The students answered various questions, some of which were intentionally misleading. Later the researchers asked all the students what they had seen—a stop sign or yield sign?

To Nader and his colleagues, the experiment supports the idea that a memory is re-formed in the process of calling it up. Hardt and Nader say something similar might happen with flashbulb memories. People tend to have accurate memories for the basic facts of a momentous event—for example, that a total of four planes were hijacked in the September 11 attacks—but often misremember personal details such as where they were and what they were doing at the time.

Hardt says this could be because these are two different types of memories that get reactivated in different situations. Television and other media coverage reinforce the central facts. But recalling the experience to other people may allow distortions to creep in. Some experts think he is getting ahead of himself, especially when he makes connections between human memory and these findings in rats and other animals.

Daniel Schacter, a psychologist at Harvard University who studies memory, agrees with Nader that distortions can occur when people reactivate memories. The question is whether reconsolidation—which he thinks Nader has demonstrated compellingly in rat experiments—is the reason for the distortions. Alain Brunet, a psychologist, is running a clinical trial involving people with post-traumatic stress disorder PTSD.

Where are memories stored in the brain?

The hope is that caregivers might be able to weaken the hold of traumatic memories that haunt patients during the day and invade their dreams at night. Brunet knows how powerful traumatic memories can be. He decided to study traumatic stress and how to treat it. Even now, Brunet says, the drugs and psychotherapy conventionally used to treat PTSD do not provide lasting relief for many patients.

The drug, propranolol, has long been used to treat high blood pressure, and some performers take it to combat stage fright.